Role of non-acid reflux in patients with non-erosive reflux disease

نویسندگان

  • Georgios P. Karamanolis
  • Radu Tutuian
چکیده

Non-erosive reflux disease (NERD) is the most common presentation of gastroesophageal reflux disease. Although acid reflux is the most important cause of symptom generation in NERD patients, non-acid reflux is also associated with reflux symptoms. The temporal relation between symptoms and reflux episodes is of importance in evaluating the results of combined pH-impedance monitoring in NERD patients. Mucosal hypersensitivity and mechanical stimulation due to great volume of non-acid reflux are among the putative mechanisms of symptom generation.

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عنوان ژورنال:

دوره 26  شماره 

صفحات  -

تاریخ انتشار 2013